[2] Carrillo Puerto was born in the town of Motul, Yucatán, 45 km northeast of Mérida, and was of partly indigenous Maya background; he was rumored to be a descendant of the Nachi Cocom dynasty of Mayapan.

[4] Carrillo Puerto then began publishing and editing El Heraldo de Motul, which was briefly closed down in 1907 by the authorities for "insulting public officials".

[5] In the Yucatán gubernatorial election of 1909, Carrillo Puerto supported the candidacy of the poet Delio Moreno Cantón in the three-way race against the Antirreeleccionista Party's (Maderista's) José María Pino Suárez, and the pro-Díaz Enrique Muñoz Arístegui.

[7] In 1923, he had a romance with a United States journalist, Alma Reed of San Francisco, California, which was commemorated in the song commissioned by him: "Peregrina", written by the poet Luis Rosado de la Vega and the composer Ricardo Palmerín.

[9][12][13] Carrillo Puerto was not a supporter of the Adolfo de la Huerta rebellion against President Álvaro Obregón, and General Plutarco Elías Calles.

As a result, he was captured by rebel army officers, tried by a military tribunal, and executed by a firing squad on 3 January 1924, along with three of his brothers, Wilfrido, Benjamin, and Edesio, and eight of their friends.