As a defense attorney, he is lead counsel for Jaime Paule, principal witness in the so-called Fertilizer Fund Scam hearings[12] held before the Senate Blue Ribbon Committee in 2009.

He was lead defense Counsel for Lope Jimenez,[13] one of the principal accused in the Ruby Rose Barrameda Murder Case, who was consequently excluded from the Information by the Department of Justice.

[20] As a public interest lawyer, he was one of the Petitioners in the Supreme Court case of Topacio v. House of Representatives which questioned the so-called "One Hundred Thousand Peso Hocus-Bonus" of Congressmen in 1991, where he succeeded in having the members of the House return their "Christmas bonuses" and obtained a pronouncement from the Supreme Court that such "bonuses" cannot be granted to Congressmen.

Maria, he was part of the legal team that defended former President Corazon Aquino and others in a civil case, the so-called Mendiola Massacre.

Topacio himself paid the 2 million peso bond required by the Supreme Court after it issued a temporary restraining order on November 15, 2011, allowing the former president to leave the country.

Arroyo was subsequently cleared of the charges but the former president was indicted and arrested on November 18, 2011, in her hospital bed not withstanding a Temporary Restraining Order from the Supreme Court.

[29] On July 25, 2012, however, she was granted bail by the Trial Court and released from hospital detention at Veterans Memorial Medical Center.

[35] In March 2013, Topacio was asked to represent her, before the Supreme Court, in a plunder case filed against her and her son, incumbent Camarines Sur Congressman Dato Arroyo in connection with the Libmanan-Cabusao Dam Project.

He also appears for Mrs. Arroyo in a civil suit for damages in connection with the Maguindanao Massacre filed by the heirs of some of the victims thereof, represented by Atty.

He also represented Mrs. Arroyo in a new plunder case against her and Taipan's Andrew Tan and George Yang among others, concerning the Lucky Chinatown in Binondo, Manila before the Ombudsman.

He was counsel of teen star Yasmien Kurdi[42] in a string of sexual harassment cases against another actor Baron Geisler[43] in 2009, and of actress Angelica Jones in her electoral protest for a seat in the Provincial Board of Laguna (1st District) in 2007.

On October 11, 2011, the case against Baron Geisler was settled amicably after he publicly apologized to Yasmien Kurdi in a press conference.

[45] In July 2013, his legal services were also secured by multi-awarded actress Claudine Barretto, dubbed by entertainment press as "The Optimum Star," to represent her in petition for temporary protection order (TPO), permanent protection order (PPO) and custody of her children against her husband, actor Raymart Santiago, before the Marikina Regiona Trial Court.

[60] On September 16, 2014, upon Topacio's application, Cornejo and co-accused, Cedric Lee and Simon Raz, were granted bail by the Trial Court.

In July 2014, Topacio assisted Heartthrob Aljur Abrenica in filing a suit against GMA7 to compel the latter to rescind his contract with the studio citing "lack of respect and "mismanagement".

[62] On March 10, 2015, however, Topacio withdrew as Abrenica's counsel saying that certain key officials of GMA Artist Center has made their withdrawal a condition for entertaining talks of reconciliation with Mr.

He is vice president of the SulongBayan Movement and a lifetime member of the Philippine Constitutional Association (Philconsa) and the Circulo Caviteño, He is the head of the legal panel for the Volunteers Against Crime and Corruption (VACC).

LTA, Inc. is a diversified company that has interests in real estate leasing, health care, power generation and financial services, among others.

[69][70] The group appealed the decision to the Supreme Court, which issued a status quo ante order allowing PASANG MASDA to participate in the 2013 elections pending resolution of its petition.

[74] On April 4, 2013, during a LADLAD fund-raising affair at the Rembrandt Hotel, Topacio was proclaimed by the group's leadership as the country's first "Honorary Gay."

[82] Its initial venture is a big budgeted feature film based on the true story of the so-called SAF 44 simply entitled Mamasapano, which stars Edu Manzano, Claudine Barretto, Aljur Abrenica, JC De Vera, Allan Paule, Ritz Azul, Gerald Santos, Myrtle Sarrosa and other well known actors and actresses.

[83][84][85] On November 28, 2020, Borracho Film successfully produced 2012 PBB Teens Grand Winner Myrtle Sarrosa's first major concert, Still Love Me which was streamed online due to the pandemic.

[86][87][88] While Mamasapano is still filming, Borracho is also producing Claudine Barretto's comeback movie with multi-awarded director, Joel Lamangan at the helm.

[90] On July 1, 2016, Topacio acted as counsel for the families of the policemen who were victims of the Mamasapano clash, where on January 25, 2015, 44 troopers belonging to the Special Action Force of the Philippine National Police were slain in a chance encounter with Muslim rebels in Maguindanao after a successful operation against terrorist Zulkifli Abdhir (also known as Marwan)[91][92][circular reference] On behalf of the families, Topacio filed the first lawsuit on the said date against former President Benigno Aquino III, whose term ended the previous day, for reckless imprudence resulting to multiple homicide.

Included in the suit are former generals Getulio Napeñas (then SAF Commander) and the suspended PNP Chief Alan Purisima[93][94] After reaching the Supreme Court on some technicalities, the victims, through Mayor Benjamin Magalong, tried to reopen the case.

[95][96] In December 2017, Topacio was instrumental in opening a probe against former President Benigno Aquino III and Department of Health Officials over hundreds of child deaths caused by the "undue haste" in administering Dengvaxia, an untested Dengue Vaccine to almost a million school children.

[105] He was born and raised Aglipayan before converting to INC.[106] Topacio had hung in his office wall a portrait of Adolf Hitler, whom he regards as a leader who improved Germany and "one of the most misunderstood historical figures" in the world while denying his role in the Holocaust.

[111] However, he has used faggot as a slur against then Presidential Communications Development and Strategic Planning Office (PCDSPO) undersecretary Manuel Quezon III in 2012 on his blog.