Caldeiro was born on June 12, 1958, in Buenos Aires, Argentina, but considered New York City and Merritt Island, Florida, to be his hometowns.

In this capacity he was the Rockwell International design center representative for the ground processing and launch of the Orbiter Discovery.

Caldeiro was hired by NASA KSC in 1991 as a cryogenics and propulsion systems expert for the safety and mission assurance office.

He was also tasked by KSC management to undertake several special assignments where he served as the Executive Staff Assistant to the Director of Safety, Reliability and Quality Assurance.

In that capacity he was involved in all aspects of design and manufacturing reviews for the MPLM, Node 2, Columbus Module and Cupola as well as equipment fit checks.