A longtime member of the Colombian Conservative Party, Londoño served as the 1st Minister of the Interior and Justice of Colombia from 2002 to 2004 during the Administration of President Álvaro Uribe Vélez.

[1] Londoño survived the terrorist attack, but the blast killed his driver and a police escort.

[2][3] On 7 December 1968 Londoño married colleague and fellow alumni, Patricia,[4] He remarried in 1978, this time to María Margarita Camargo Espinosa.

[6] On 12 July 2002, then President-elect Álvaro Uribe Vélez ratified Londoño as his choice for Minister of the Interior.

[7] Upon taking office on 7 August 2002, Uribe sworn in his new Cabinet and Londoño as the 8th Minister of the Interior entrusting him with the Ministry of Justice and Law as well.