Fernando Niño y Zapata (died 1552) was a Roman Catholic prelate who served as Patriarch of West Indies (1546–1552),[1] Administrator of Sigüenza (1546),[2] Archbishop of Granada (1542–1546),[3] and Bishop of Orense (1539–1542).

[5][6] On 18 Aug 1539, he was appointed during the papacy of Pope Paul III as Bishop of Orense.

[5] On 22 Mar 1542, he was appointed during the papacy of Pope Paul III as Archbishop of Granada.

[3][5] On 8 Oct 1546, he was appointed during the papacy of Pope Paul III as Patriarch of West Indies and Apostolic Administrator of Sigüenza.

[1][5] While bishop, he was the principal consecrator of Pedro Guerrero Logrono, Archbishop of Granada (1547) .