As with other members of the genus Ficus, the flowers require a particular species of fig wasp to pollinate it in a co-evolved relationship.

The natural range of F. elastica extends from Nepal in the north to Indonesia, Bhutan, Northeastern India, Bangladesh, Myanmar, Yunnan in China, and Malaysia.

In parts of India, people guide the roots of the tree over chasms to eventually form living bridges.

Ornamental hybrids (such as Robusta) have been derived from Ficus elastica with broader, stiffer and more upright leaves than the wild form.

All parts of the plant contain an abundant milky white latex, a chemical compound separate from its sap and carried and stored in different cells.

[citation needed] Just as with Hevea brasiliensis, the latex of Ficus elastica is an irritant to the eyes and skin and is toxic if taken internally.