The game has the player control Simon, a man who is attempting to win an illegal fighting tournament to help get his father out of trouble with a crime lord.

Fighters Uncaged is a single-player-only fighting game controlled using the Kinect, a motion sensing input device.

The player controls the protagonist of the game, Simon, through his attempts to win an illegal fighting tournament to help get his father out of trouble with a crime lord.

In the early stages of Fighters Uncaged, it is made less difficult to read the telegraphs of the opponent, but as the player progresses, they become increasingly imperceptible.

Good scores are attained by accomplishing counterattacks, exploiting the enemies' weak spots, and correctly completing combos.

Because the announcement came suddenly and close to the release date, video game journalists such as Christopher Grant of Engadget and Jamin Smith of VideoGamer.com were not intrigued.

[3] Critics believed that the motion control system in Fighters Uncaged did not work and that the fighting mechanic was poorly made.

[2] Smith compared the combat to that of the luck in rock, paper, scissors, noting that "90% of the time" the attack will be avoided or blocked, while for the other 10%, the character "just stands there like a lemon, refusing to acknowledge the command".

[3] Jack DeVries thought that when in a fight, the moves become a "series of desperate flails" in an attempt for the game to notice the player's actions.

[16] She said that her enthusiasm for the game diminished with the intro movie, and criticized the "static images of ugly men with stupid names rolling across the screen".