Fire and Stone is a comic book series crossover set in the fictional universe of the Alien vs.

The comic book series is considered part of the extended universe of the Alien and Predator franchises, being set after the events of Prometheus.

Francis, a scientist on the survey team, and synth Elden find discovery notes on the black goos power to cause rapid evolution.

Dying of cancer, Francis injects the black goo into Elden to visualise what the effects would be.

The remaining survey team survivors Angela and 2 others then set off to safety where Francis originally discovered a base camp of scientific information regarding the black blob and relax.

As the Xenomorphs ravage the colony, engineer Derrick Russell and greenhouse specialist Genevieve Dione attempt to lead other colonists to safety.

The survivors enlist the help of Nolan Cale, a scavenger and pilot in possession of a small freighter known as the Onager.

While the colonists board the freighter, Cale notices several xenomorphs that manage to stow away aboard one of the ship's cargo bulkheads.

However, afraid of being marooned on LV-426 should he remain behind to decouple the infested cargo bulkhead, Cale abstains from informing the survivors and gives the all-clear for the ship to depart.

However, the colonists inadvertently unlock the infested cargo bulkhead, and the concealed xenomorphs emerge, killing some of the survivors.

As the survivors' numbers dwindle, Dione, becoming the group's self-appointed leader, urges that they erect defenses and frequently seek safety whenever possible.

However, Cale dissents and insists that the remaining survivors mount an offensive to reclaim the supplies from the Onager and kill the xenomorphs.

Russell continues to compile his findings in a cave situated within a mountain that the xenomorphs are wary of approaching.

As the group endeavors to survive by scavenging for food, a few of the members on a fishing excursion at a lake are attacked by xenomorphs.

One of the survivors, Luis, is dragged beneath the lake after a scuffle with a xenomorph and in the process, both are fused together as one organism- a product of the black substance that Russell is investigating.

An enraged Dione berates him for his incompetence, but Cale vows to redeem himself by leading a group of survivors to attack the xenomorphs guarding the Onager and recovering the distress transmitter.

Russell, now the sole remaining member of the group, continues to take refuge in his cave and focuses on his studies of the LV-223 environment.

However, as the days pass, he becomes increasingly unstable and erratic from weeks of isolation, and a diagnosis from the probe reveals that he is afflicted with brain tumors.

The struggle attracts the attention of the xenomorphs, and as Russell attempts to flee, he becomes injured and is unable to reach his mountain hideout.

Elden then uses the capital ship to remotely power down systems on the shuttlecraft piloted by Galgo and requests Francis as ransom.