The book follows Daunis Fontaine, a half-native, half-white young adult who witnesses her friend's murder and becomes involved in an FBI investigation revolving around a new drug.

[6] Kristina Pino, writing for Booklist highlighted how Boulley "doesn’t shy away from or sugar-coat the very real circumstances that plague reservations across the country.

The author's love for and connection to her culture is so deeply engraved into the very heart of this book and it beats in rhythm with each new plot development.

"[18] They further stated that "her voice is young and earnest and her fluency adds to the portrayal of Daunis ... LaBlanc’s sensitive reading will keep listeners plugged in.

"[18] Barack and Michelle Obama's production company, Higher Ground, purchased the rights to adapt Firekeeper's Daughter into a TV series, which will be released on Netflix.