First Lady is a 2022 Philippine television drama romance comedy series broadcast by GMA Network.

Directed by L.A. Madridejos, it stars Sanya Lopez in the title role.

It premiered on February 14, 2022 on the network's Telebabad line up.

The series concluded on July 1, 2022 with a total of 97 episodes.

[111] According to AGB Nielsen Philippines' Nationwide Urban Television Audience Measurement People in television homes, the pilot episode of First Lady earned a 14.4% rating.