It was sent to rhythmic and urban contemporary radio on February 12, 2019, as the third and final single from the former's seventh studio album, The Wizrd.
[1] The song was written by the artists alongside XO manager Cash and producer ATL Jacob.
"First Off" features a "heavy-hitting instrumental" with a "drowsy yet infectious performance by Future".
[4] The song features lyrics about money, drugs, and the NBA, and includes references to players such as Dwyane Wade, James Harden, and Tracy McGrady.
Malvika Padin of Clash wrote that Travis Scott's strong performance on the track "lifted the [album]" much like Gunna's feature on "Unicorn Purp".