The Shehbaz Sharif government was formed on 10 April 2022, after Sharif was nominated as candidate for Prime Minister by opposition parties following a vote of no confidence in incumbent prime minister Imran Khan during the 2022–2023 Pakistan political unrest.

[3][4] At the time of appointment, he had the majority 85 seats in the ruling alliance of 179 MNA from eight political parties and independent candidates.

[10][11][12][13] If Advisers and Special Assistants included, the cabinet is reportedly the largest in Pakistan's history.

[14][15] In a February 2023 article reporting on further appointments,[15] The News International noted the high number of special assistants serving without portfolio.

Planning, Development and Special Initiatives Interior Federal Education and Professional Training Railways and Aviation Law and Justice Power Human Rights Parliamentary Affairs Finance, Revenue and Economic affairs Water Resources Commerce Climate Change National Health Services, Regulations and Coordination Poverty Alleviation and Social Safety Industries & Production Overseas Pakistanis and Human Resource Development Inter Provincial Coordination Privatization Foreign Affairs Communications Housing and Works States and Frontier Regions Information Technology and Telecommunication Maritime Affairs Defence Production Narcotics Control National Food Security and Research Board of Investment Science and Technology