[6][7][8] Her maternal grandfather, Mario Mastrocola (1914–1978), was an Italian bassoon musician, who naturalized as a Swiss citizen in 1960.

[9][10] She has two younger brothers and was raised in the hamlet of Hinterkappelen (part of Wohlen bei Bern).

In 1998, Wasserfallen completed her Matura, at Gymnasium Bern-Neufeld, followed by a gap year spent working as a snowboard teacher.

[16] She advocates for better working conditions in relation to the patients[19] and she is the president of the Mother and Father Counseling Association.

[20] In September 2020, she was a co-founder of FC Helvetia, the female football team of the Swiss Parliament.