[4][5][6] Chambers reportedly started swimming around 1917 for therapy from a spinal injury she received from a streetcar accident in Los Angeles around the age of nine.

[14] She lowered her own 100-yard Pacific Coast backstroke record in Los Angeles on October 29, 1925, with a time of 1:21, and also won the state championship in the 100-yard freestyle.

[17] Soon recognized as a regional leader in competitive swimming, the Florence Chambers Club took a silver trophy, scoring the second largest number of combined points at the Far Western Aquatic Championship in August 1928 in Long Beach.

[18] Continuing to field entries, Chambers' Club had numerous participants in the 1929 Southern Pacific Association AAU Aquatic Championships on June 2, 1929, in San Clemente.

Norene Forbes, another one of Florence's outstanding swimmers, won the Silver Gate Swim twice, as well as the two-mile Hermosa Beach Roughwater event.

[22][23] By 1950, Chambers had taken a break in coaching her swim club and was beginning to focus on community work, though she would continue to instruct swimmers individually and in smaller groups at various times in her later life.

Chadwick won the Los Angeles Hermosa Beach Roughwater Swim in June 1933, a competition in which her coach Florence Chambers placed fifth.

[27] She represented her own club in Women's competition at the July 3, 1930 National AAU Swimming Championships in Long Beach, California.

A supporter and patron who took an interest in the way Brigham Young University developed character in its students, she received a Presidential Award from the college "in appreciation of extraordinary service".

[6] Shortly before her death, she bequeathed her ranch, then with an estimated value of around 5 million dollars to Brigham Young University and gave another large donation to the San Diego Historical Society.