The Sioux City Women and Babies Home Association was incorporated on October 21, 1897.

The purpose of the organization was to aid the "friendless, dependent women and girls, and may receive and dispose of babies of deceased fathers or mothers, or those abandoned by them, or those surrendered to this corporation by the order of any judge, court or officer, or legal guardian.

In the early years, many of the young women kept their babies, but adoptions became more prominent by the mid-20th century.

The Crittenton Center determined the 1906 building no longer served its needs, and they moved to a new facility in 1998.

This article about a property in Woodbury County, Iowa on the National Register of Historic Places is a stub.