He later made his senior Grand Prix debut at the 2009 Cup of Russia, where he placed 9th, and came in 4th at the 2009 Skate America, missing out on a medal by less than a point.

Amodio won the French national title in December 2009 and was selected for the Olympic and World team.

In May 2010 Amodio made a coaching change, leaving Bernard Glesser, who had trained him since childhood, to work with Nikolai Morozov in Russia and Latvia.

[13] At the 2011 French Nationals he had a disappointing short program but moved up to win silver behind Brian Joubert after a strong showing in the free skate.

He was third in the free program and finished with a combined total of 226.86 points, 3.85 ahead of Joubert, to win gold in his European debut.

[18] In the off-season, Amodio skated in shows in Korea, saying that it was a good source of income: "Finally, I could start making a living with what I loved!

[21] He also worked with Alexei Yagudin on quad toes in the U.S.[22] He won the 2011 French Masters event in October.

He announced that he would return to training with former coach Bernard Glesser when he was in France, and spent the time after the Grand Prix Series reworking his programs.

At the World Championships in Nice, he placed 6th after the short program, and rose to finish 5th overall with a free skate score of 163.07.

His placement combined with Brian Joubert's 4th-place finish earned France three spots in the men's competition for 2013.

In the 2012–13 Grand Prix season, Amodio was assigned to 2012 Skate Canada International and 2012 Trophée Eric Bompard, finishing 4th and 2nd.

[27] After the event, he skated in twelve shows in two weeks as part of the Art on Ice tour in Switzerland, Finland, and Sweden.

[32] On 23 July 2013, he confirmed the end of his collaboration with Morozov and that he was training in Paris with Katia Krier as a temporary arrangement.

"[38] Amodio finished sixth and seventh at his two Grand Prix event assignments, the 2013 Cup of China and the 2013 Trophée Eric Bompard.

At the event in Budapest, Hungary, he ranked seventh in the short program and 20th in the free skate, finishing 13th overall and the lowest-placed of the three French men.

For the 2015–16 Grand Prix season, Amodio was assigned to Skate America and the Trophée Eric Bompard.