The freeway travels almost due north–south entirely within the neighborhood of Jacksonville known as Arlington.

This is completely within the city limits of Jacksonville, in Duval County, in the U.S. state of Florida.

It heads northeast and travels along the west edge of Regency Square Mall.

At Tredinick Parkway, there is a Texas U-turn that allows traffic from the southbound service road to make a U-turn to access the northbound one without accessing Tredinick Parkway itself.

Almost immediately afterward, the freeway curves to the northwest and feeds into I-295 north.