[4] In 1960, his piano instrumental solo, "Last Date" went to number two on the Billboard Hot 100 pop music chart and sold over one million copies.

After finishing high school, he returned to Shreveport, where he worked as a ragtime pianist for the radio show Louisiana Hayride, with a banjo-bass-and-drums combo.

His earliest recordings, on the Abbott label, carry the credit "Featuring Floyd Cramer on the Piano with Louisiana Hayride Band".

After Elvis Presley performed on Louisiana Hayride in 1955, he hired his own band which included Cramer, Jimmy Day, Scotty Moore, Bill Black, and D.J.

[6] Before long, he was one of the busiest studio musicians in the industry, playing piano for stars such as Elvis Presley, Brenda Lee, Patsy Cline, the Browns, Jim Reeves, Eddy Arnold, Roy Orbison, Don Gibson, and the Everly Brothers, among others.

While Cramer was well-established as a session player, he had a long career as a solo performer with dozens of his own albums and singles, including some Top 40 instrumental hits.

By the mid-1960s, Cramer had become a respected performer, making numerous albums and touring with guitar maestro Chet Atkins and saxophonist Boots Randolph, sometimes headlining and sometimes as the opening act for Eddy Arnold.

Cramer’s grandson, Jason Coleman, followed in his footsteps taking up the piano, performing with him on television and in concert at a young age.