Providing service for the Blue, Orange, and Silver Lines, the station is located on I Street on the George Washington University (GWU) campus.

[2] Its opening coincided with the completion of 11.8 miles (19.0 km)[3] of rail between National Airport and RFK Stadium and the opening of the Arlington Cemetery, Capitol South, Crystal City, Eastern Market, Federal Center SW, Federal Triangle, L'Enfant Plaza, McPherson Square, National Airport, Pentagon, Pentagon City, Potomac Avenue, Rosslyn, Smithsonian and Stadium–Armory stations.

In 2008, WMATA installed red-colored LED lights at Foggy Bottom–GWU and other busy stations after a successful pilot at Gallery Place.

[8] Escalators from here allow passengers to descend to platform level or to the sole entrance and exit of the station at the northwestern corner of I and 23rd Streets.

[10] In 2007, WMATA released a report detailing the potential to add a second entrance to the east side of the platform, serving the intersection of 22nd and I streets.