Starting in 1960, the railway underwent numerous modernisations: it was electrified, the equipment was replaced and the main station squares were rebuilt.

However, the branch to Tavernelle (Panicale), which connected to the line at Ellera-Corciano station was closed due to low traffic.

[10] Over time, the line has continued to play the role of connecting the Florence–Rome and the Rome–Ancona lines, frequented mostly by regional trains of various compositions and railcars of the Ferrovia Centrale Umbra, as well as by trains running directly between Perugia and Rome via Foligno.

It begins in the Tuscan territory with a two-kilometre straight from Terontola station and, after a couple of short tunnels, turns south-east reaching Tuoro station; it continues alongside Lake Trasimeno, following its profile and passing by Montecolognola with the longest tunnel of the line, about 1.3 km long, and reaching Magione; it then runs to Ellera, including a long stretch on an embankment.

The third section, about 28 km long, runs from Ponte San Giovanni to Foligno and is characterised by a totally flat area and an almost straight line, except for some bends near the towns.