The film introduces popular night clubs and sex venues from all around the world, including Las Vegas, Tokyo, Paris and Africa.
It stars Amanda Lear, at the time at the peak of her international career as a disco singer, who acts as a guide, introducing cities and describing what they have to offer in terms of night life.
The film includes such sexual activities as sadomasochism, necrophilia and group sex, in addition to erotic dancing and magic tricks with the use of nudity.
In addition, Amanda Lear performed two of her songs in the film: "Follow Me" in one of the opening scenes, and "Enigma (Give a Bit of Mmh to Me)" in the finale.
In the German version, Mondo Erotico, Amanda Lear songs were replaced with a different music and the performance of "Enigma" heavily edited.