[1][3] Folsom Boulevard begins in the East Sacramento neighborhood (in a southeasterly direction) as a two-lane roadway, expanding to four lanes at 59th Street.

After passing the intersection of 65th Street, Folsom Boulevard is reduced to two lanes as it runs beneath the Union Pacific railroad tracks via a short subway tunnel.

Folsom Boulevard intersects Howe Avenue and Power Inn Road, overlapping State Route 16 for roughly 1/2 mile (0.8 km).

As it reaches Watt Avenue, Folsom Boulevard leaves the city of Sacramento and into the unincorporated suburb communities of La Riviera and Rosemont.

It begins to closely parallel US 50 until it intersects Hazel Avenue, leaving Rancho Cordova en route to the city of Folsom.