It is found in southeastern Queensland, Australia, extending from Boyne Valley to Cedar Creek and is considered vulnerable due to several contributing threats (fire, urban development, and weed infestation).
[10] F. venosa also shares similar genetics to Fontainea picrosperma and may contain the drug EBC-46, which has been found to be effective for patients coping with cancer.
[5][6] F. venosa was first formally described in 1985 by Laurence W. Jessup and Gordon P. Guymer in the journal Austrobaileya from specimens collected at Bahr's Hill, south of Beenleigh in 1984.
[9] A study that examined the presence of Cytochrome P450s (CYP450s), vital enzymes for biosynthesis of physiologically essential compounds involved in the catalysis reactions of plant growth and development via metabolome analysis, showed that Fontainea species have a unique chemical profile compared to other plant species.
[10] The result also indicated that F. picrosperma and F. venosa are closely related species and possibly share similar arrays of natural products including epoxytigliane diterpenes (EBC-46) or tigilanol tiglate.
Both species (F. venosa and F. picrosperma) also share some clans of CYP450 genes, such as CYP71 which is classified to have a strong potential of being "key enzymes in the biosynthesis of diterpene esters of epoxy-tigliane class," for medicinal purposes.
[10] F. venosa occurs in few locations in Queensland, ranging from Beenleigh North near Brisbane, alongside Koolkooron Creek in Boyne Valley, near Littlemore and to Brooyar State Forest next to Nargoorin.
[18] Threats include habitat destruction due to urban and agricultural development in a majority of vine forests where it naturally occurs, particularly nearby Bahr's Scrub, Beenleigh[19] and exotic weed infestation, including Rivina humilis, Lantana camara and Passiflora subpeltata, that hindered F. venosa germination and seedling growth, particularly in SF 82 (Brooyar).
[6] Other management actions include; assembling responsible seed collection; storage and facilitate appropriate sites for recovery; raising awareness of F. venosa to both local and regional communities, and constructing a protective buffer (0.3 ha) at least 30m away around the areas of vine forest and vine thicket where F. venosa occurs in to prevent habitat clearance.
Results from Geographic Information System Mapping (GIS) assessment and on-ground survey in the restoration plan will identify suitable microhabitats in Belivah Creek to introduce F. venosa while conserving its site flood mitigation and recreational functionality.
[24] The project recovery plan stated that 32 plant species — including F. venosa — are endemic to Mary River and thus will be restored.
According to recently published studies and current research, EBC-46, has the potential to be an anti-cancer drug with cancer destroying properties.