Football was contested for men only at the 1978 Central American and Caribbean Games in Medellín, Colombia.

[1] Colombia was disqualified from the tournament.

Colombia won 4–0, but the result was later awarded to Venezuela Colombia drew 1–1 with Mexico, but the result was later awarded to Mexico.

Note: Colombia won 5–1, but the result was awarded to Puerto Rico on the following day, 16 July, when Colombia was disqualified due to 14 of their players being professionals.

Note: This match was not played because Colombia was disqualified.