[3] A baby boy is found abandoned in a Hell's Kitchen tenement and subsequently is raised by three men: a German delicatessen owner (Sterling), a Jewish tailor (Sidney), and an Irish street cleaner (Cameron).

The now-grown Mike (Lyon) resists going to college because he does not wish to be a financial burden to his adoptive fathers, however a pretty Italian girl, Mary (Colbert) working at the delicatessen convinces him to go.

[7] Producer Robert Kane had contracts to provide First National Pictures with 10 films, and had planned each to be financed with profits from the preceding.

[6] For the Love of Mike was the tenth in this package, funding was limited, and agent Leland Hayward convinced Capra into deferring his salary until the end of production.

It seemed to satisfy the audience at the Hippodrome yesterday afternoon, for there was laughter and, at the end, applause", and concluded "Claudette Colbert, who was seen in Kenyon Nicholson's play "The Barker," lends her charm to this obstreperous piece of work.