The Fort Henry Bridge is a crossing of the Ohio River main channel in Wheeling, West Virginia.

The bridge is the easternmost portion of a 1-mile (1.6 km) long chain of elevated structures spanning Wheeling Creek in Ohio, the Ohio River back channel, Wheeling Island, and the main channel.

[7] Every year, the West Virginia Department of Transportation (WVDOT) conducts a series of surveys on its highways in the state to measure traffic volume.

In 2009, WVDOT calculated that 60,070 vehicles used the Fort Henry Bridge over the main channel of the Ohio River.

[3][16] During the first years of the bridge it carried US 40 and US 250 from Wheeling Island over the Ohio River main channel.