In addition to its symphonic and pops concert series, the FWSO also collaborates with the Fort Worth Opera, Van Cliburn International Piano Competition, Southwestern Seminary Master Chorale.

Sixty-eight musicians performed at the first concert on December 11, 1925, before an audience of approximately 4,000 at the First Baptist Church auditorium.

In 1957, Morris again revived the orchestra, whose musicians initially performed without salary, and provided general organisational leadership.

[4] In May 2018, the FWSO announced that Harth-Bedoya was to conclude his music directorship of the orchestra at the close of the 2019–2020 season, and subsequently to take the title of conductor laureate.

The orchestra announced the appointment of Spano as its new principal guest conductor, with immediate effect, with a contract through the 2022–2023 season, at the time of his FWSO debut.

[6] In February 2021, the FWSO announced the appointment of Spano as its next music director, effective with the 2022–2023 season, with an initial contract of three years.

In December 2021, the FWSO announced the appointment of Edusei as its next principal guest conductor, effective with the 2022-2023 season, with an initial contract of 3 years.