Four Blind Mice is the eighth novel featuring the Washington, D.C. homicide detective and forensic psychologist Alex Cross written by James Patterson.

[1] The novel features Washington D.C. Metro Police homicide detectives Alex Cross and John Sampson as protagonists.

In the course of the investigation, Cross and Sampson discover that three Army Rangers had committed similar crimes during the Vietnam War.

The three Rangers, nicknamed "The Three Blind Mice," (Thomas Starkey, Brownley Harris, and Warren Griffin) had performed a series of unauthorized killings of unarmed villagers and subsequently painted the bodies red, white, and blue.

Another victim, Colonel Handler, had discovered the plot and was killed so as to not jeopardize Hutchinson's candidacy for the Joint Chiefs of Staff.