[1] Student at the lycée du Mas de Tesse in Montpellier, where he was awarded the French Baccalauréat,[2] Mion went on to classes préparatoires at the Lycée Henri-IV, before integrating the École normale supérieure from which he graduated in 1988.

[3][4] Frédéric Mion then studied Public Affairs at Sciences Po, earning a Master's degree in 1992.

[5] After a brief period at Princeton University, he joined the École nationale d'administration (ENA), from which he graduated first in his class of the promotion Victor-Schœlcher in 1996.

In January 2021, it was revealed he knew about child abuse for 2 years before it was published in a book that brought it to international attention.

[6] In February 2021, in light of new details emerging from the Duhamel affair, Mion resigned as Director of Sciences Po.