[9] Asselineau started his career in Japan in the department of economic expansion for National Service Overseas (CSNE).

In 1991, he became chief of mission of the Asia-Oceania office at the Direction of Foreign Economical Relation (DREE) in the Ministry of Economy and Finance under the Pierre Bérégovoy government.

In 1996, he moved to the ministry of Foreign Affairs, where he was in charge of economic matters for Asia, Oceania and Latin America until the dissolution of parliament by Jacques Chirac in 1997.

In 1999, François Asselineau got involved in politics by becoming a member of the Rally for France (RPF), a party created by Charles Pasqua and Philippe de Villiers.

On October 20, 2004, Nicolas Sarkozy appointed Asselineau as the director of the general delegation for economic intelligence within the Minister of Economy and Finance.

[13] His campaign was marked by a radical rhetoric on security, with posters denouncing "six years of socialist laxity", supposed drug trafficking, alleged prostitution and an asserted lack of police forces.

[14] On December 31, 2004, Asselineau decided to join the group Union for a Popular Movement (UMP) at the Council of Paris.

[15] On November 3, 2006, he decided to quit the group and seat with the non-inscrits just after Françoise de Panafieu, for whom he worked, was elected president of the council of Paris for the Union for a Popular Movement (UMP).

[16] In September 2007, Asselineau participated in a dissident political group named Paris Libre with several other ex-UMP members.

[32] According to Asselineau, the EU and NATO "as seen from Washington...are the political and military side of the same coin, that of the enthrallment of the European continent to their 'buffer zone' so as to surround and contain the Russian continental power".

[34] He said on the French TV program On n'est pas couché that he opposes military intervention in Syria and Iraq.

[3][7]: 27'45" Asselineau claims the 1944 Conseil national de la Résistance as the source of inspiration for his presidential program in 2012, including "re-nationalisations" and "quality public services".