[1] He was born at Marmande, made his preliminary studies in the Jesuit College at Bordeaux, and joined the Dominican Order in 1624.
He published successively the works of Amphilochius of Iconium, of Methodius of Olympus, and of Andrew of Crete, together with some writings of John Chrysostom not yet in print.
The Historia haeresis monothelitarum sanctaeque in eam sextae synodi actorum vindiciae, which formed part of the historical section of this work, met with much opposition in Rome, principally because it was at variance with the opinions of Bellarmine and Baronius.
In 1656 he edited John Chrysostom's De educandis Liberis, in 1660 a collection of Acts of the martyrs.
in S. Mariae Dormitionem et Translationem oratio historica, and in the same year an edition of the works of Maximus Confessor in two volumes with a Latin translation.
Perhaps the most important of the works of Combefis is his edition of Basil of Caesarea in two volumes, Basilius magnus ex integro recensitus, textus ex fide optimorum codicum ubique castigatus, auctus, illustratus, haud incerta quandoque coniectura emendatus.