Born into a prominent noble family from the Massif-Central, Entragues began his career serving as an officer in the company of the duke of Longueville.
He thus aligned with the duke of Guise and the Catholic ligue in the succession crisis that began in 1584 upon the death of the king's brother Alençon.
When the ligue went to war with the king in 1585 in opposition to his chosen heir, his Protestant cousin Navarre, Entragues entered rebellion with them.
He attempted to support the king in the Estates General of 1588 with the selection of royalist deputies, but was outmanoeuvred by the ligueur elite of the city.
With the assistance of her parents she evaded his attempts initially, the family deciding they wanted to hold out until receiving financial reward.
With Jacqueline de Rohan they had:[1] With Marie Touchet they had:[1] Entragues was a major landholder in the Île-de-France, with lordships over Marcoussis, La Ville-du-Bois, Boissy, Saint-Yon, Breux, Breuillet, Châtres and Nozay.
[8] During the long peace between the first and second civil war, Entragues served as guidon of the company of the duke of Longueville, though this role terminated in 1565.
[1] With the death of the king's brother in July 1584, the Lorraine family took the opportunity to found a new Catholic ligue in opposition to the succession of the Protestant Navarre.
The duke of Guise opened hostilities by taking control of Châlons, meanwhile his brother Mayenne captured Dijon and Auxerre and cousin Mercœur rose up in Bretagne.
Entrenching himself in the city he would greet the royalist troops with cannon fire and successfully rebuff Montpensier from taking the citadel on 21 April.
[15] Entragues had moved out Orléans and joined forces with the ligueur La Châtre and Brissac to besiege the Protestant held town.
Épernon was dispatched to relieve Gien and left Paris to that effect on 30 May, successfully driving away the ligueur army without battle on 3 June.
[19] Henri's re-acquisition of Entragues was enabled by the financial difficulties the noble was in, unable to support his position in Orléans and finding himself increasingly unpopular in the city.
Entragues’ brother Entraguet was dispatched to entreat with him, and spent a month in the city working to persuade him to come to Marcoussis where the king had an offer for him.
On 13 May, with the king backed into his palace Guise wrote to Entragues in the early hours of the morning to urge him to come to the capital, and bring as many of their allies as they could muster.
His resolve in this respect was bolstered when Entragues visited him secretly to assure him of his loyalty and his willingness to hand over the city of Orléans to the king.
His more realistic hopes for securing the loyalty of the city relied on Entragues diplomatic and military skills and several royalist notables within the walls.
[27][32] During January the siege of the citadel continued, Mayenne, lieutenant-general of the ligue came to direct the bombardments, he took the opportunity to appoint his cousin the chevalier d’Aumale as the cities governor in opposition to Entragues.
[33] It was decided that the citadel which represented royal tyranny over the urban privileges of the city should be dismantled, a process which was completed on 7 April.
Auvergne was to live out the rest of his life in the Bastille, Entragues was put under permanent house arrest and Morgan was expelled from France.
[37] With the Assassination of Henri IV in 1610, some suspicions turned to Entragues and his daughter as having had involvement in the killing, in particular after the Prévôt de Pluviers was found dead in his cell.