At the beginning of the 21st century, she performed music of Heitor Villa-Lobos, directed by Isaac Karabtchevsky, and has collaborated with the great Brazilian singer and songwriter Gilberto Gil.

Her performances of works of North Americans Oscar Peterson, Dave Brubeck, Aaron Copland, George Gershwin, Leonard Bernstein have had great success in duet recitals with Mauro Maur.

She has played concerts in Italy, Vatican, France, Belgium, Germany, Spain, England, Switzerland, Luxembourg, Austria, Slovenia, Croatia, Bosnia, Montenegro, Serbia, Spagna, Portugal, Sweden, Russia, Kazakhstan, Turkmenistan, Latvia, Georgia, Hungary, Romania, Czech Republic, Poland, Argentina, Brazil, Bolivia, Peru, Chili, Colombia, Venezuela, Panama, Guatemala, Mexico, Canada, United States, Saudi Arabia, Kuwait, Turkey, Armenia, Lebanon, Tunisia, Libya, Morocco,[1] Eritrea, Ethiopia, Egypt, Nigeria, Gabon, Congo, Zambia, Mozambique, South Africa, Malesia, Thailandia, Singapore, Japan and China.

Françoise de Clossey has attended the University of Montreal, the Conservatorio Santa Cecilia in Rome and the MusicaRiva Festival.

[2] Françoise de Clossey was honoured with the International "Beato Angelico" Prize for the Woman of the year 2006.