Born in La Solana, Ciudad Real, Castile-La Mancha, Manzanara was a Valencia CF youth graduate.

In 2014 he joined Atlético Madrid, and made his senior debut with the C-team on 7 September 2014, starting in a 5–1 Tercera División home rout of AD Colmenar Viejo.

Manzanara scored his first senior goal on 2 November 2014, the equalizer in a 3–1 home win against CD Puerta Bonita.

[2] Manzanara made his first team – and La Liga – debut on 24 November 2018, coming on as a late substitute for Sanjin Prcić in a 2–2 away draw against SD Huesca.

[4] Manzanara scored his first professional goal on 22 December 2019, netting his team's second in a 3–2 away win against UD Almería.