Although she starred in many productions, she is best known for her portrayal of Alice Horton on the NBC daytime soap opera Days of Our Lives from its debut in November 1965[3][4] until 2007.

[1][2][5] At the time of her death, she ranked fifth on the all-time list of longest-serving soap opera actors in the United States.

From 1954 to 1955, Reid played the title role in the CBS television version of the radio serial Portia Faces Life.

She next portrayed the grasping Grace Baker, the mother-in-law of Penny Hughes, on As the World Turns from 1959 to 1962, and Rose Pollack, the kind-hearted mother of Nancy Pollock Karr, on The Edge of Night in 1964.

[2][3] She won the Soap Opera Digest Award for Outstanding Actress in a Mature Role in 1978,[12] 1979,[13] 1984,[14] and 1985,[15] and was inducted into the Television Academy's archives in 2003.