Francesco Cornaro (1478 – 26 September 1543) was an Italian cardinal.

He was made cardinal on 20 December 1527 by Pope Clement VII in his fourth consistorium.

He was installed as Cardinal Priest of San Pancrazio on 27 April 1528.

In April 1534 he was appointed Cardinal Priest of Santa Cecilia in Trastevere, in September 1534, Cardinal Priest of San Ciriaco alle Terme Diocleziane and in May 1535 Cardinal Priest of Santa Prassede.

In March 1541 he was appointed Cardinal Priest of Santa Maria in Trastevere.