After the death of his mother Giovanna Giuseppa Galeano, Francesco’s father entrusted him to the care of a religious tutor of Taormina Don di Blasi who directed him in the choice of studies.

During a call for tenders related to the recruitment of a surgeon at the Santa Maria Nuova hospital in Florence, passed the test and immediately began to work.

[3] This theory is based on the hypothesis that point and random alterations of nuclear DNA would give rise to tumour clones capable of growing and metastasizing at any time.

[4] He left the Institute of Pathological Anatomy of Berlin, taking advantage of the outbreak of the Franco-Prussian War, in which he participated as head of the German Red Cross.

Durante decides to run to the front in no man's land with the risk of being hit by the opposing fire, he manages to block the bleeding and attach the stumps of the interrupted vase.

For this gesture, when the Prussian ambassador reaches Paris, he seeks Durante, to award him an honour on behalf of the King of Prussia, but does not find him.

He later attended surgery classes held in London by W. Ferguson and T. Spencer, but this stay lasts little and he observes that the sterilization of the surgical instruments takes place by boiling or by the use of dry stoves.

It is a period of intense work that sees him engaged in completing some research started abroad and published the first two years in German and the third in French, "On the Organisation of the Thrombin in the Walls of the Vessels".

It was not until 1887 at the International Congress in Washington that Durante presented two scientific contributions in English: the first on the "Creation of an Artificial Year as a Preliminary Treatment of Rectal-Colic Disease" and a second on the "Technique for Removal of Endocranial Tumors".

Since he was the only clinic surgeon in Rome, Francesco Durante decided to intensify his professional activity by reaching the aristocratic, political and royal environments.

[12] Durante was nominated Senator for Life on 26 January 1889 at the age of forty-four for his scientific achievements in the presence of King Umberto I di Savoia.

He used this opportunity to create a network of influential people around him, crucial for his future battles for reforms in academic and clinical activities with the aim to make Rome the Capital of the kingdom.

The construction of the Policlinico Umberto I was finished in 1902; it comprised forty-nine buildings connected to each other via tunnels that allowed for the separation of the patients according to their disease in order to prevent their spread inside the hospital.