He also entered the main draw at the ATP Challenger 125, the 2024 Tennis Napoli Cup this time as an alternate, and reached the semifinals.

[1] After reaching the main draw of his home Masters, the Italian Open, having received a wildcard for the qualifying competition, he defeated Arthur Rinderknech for his first Masters main draw win.

Next, he reached the third round for the first time at a Masters level, defeating 23rd seed Tallon Griekspoor.

[1] Passaro made his Grand Slam main draw debut at the 2025 Australian Open as a lucky loser after the withdrawal of his compatriot Fabio Fognini.

[7] He recorded his first Grand Slam win following the retirement of tenth seed Grigor Dimitrov due to a hip injury, and moved into the top 100 in the singles rankings.