[1] On 26 April 1478, Easter Sunday, there was an attempt to assassinate Lorenzo de' Medici and his brother and co-ruler Giuliano while both were attending High Mass at the Santa Maria del Fiore cathedral in Florence.

[5] Francesco de' Pazzi was sung by bass Ludovico Contini in the first performance of Leoncavallo's 1893 opera I Medici.

[6][7] Francesco appears as an antagonist in the video game Assassin's Creed II, voiced by Andreas Apergis.

[8] In the game, he has a son named Vieri and is a member of the Templar Order, who are depicted as the orchestrators of the Pazzi conspiracy.

Elliot Levey portrayed Francesco de' Pazzi in TV series Da Vinci's Demons.