At the age of nineteen at the siege of Port Hudson, Warren received the Medal of Honor for battlefield gallantry.

His entire platoon was destroyed by Confederate bombardment and Warren, taking a serious scalp wound, disabled the artillery.

Mrs. Warren was the president of church, literary and charitable societies of Cheyenne, vice-president of the Foundling Hospital, and Daughter of the American Revolution.

[6] Following the civil war, Warren engaged in farming and stock-raising in Massachusetts before moving to Wyoming (then part of the Territory of Dakota) in 1868.

He was reappointed by President Benjamin Harrison in April 1889, and served until 1890, when he was elected first Governor of Wyoming (October 11, 1890 – November 24, 1890).

In November 1890, Warren resigned as governor, having been elected to the United States Senate as a Republican, serving until March 4, 1893.

Warren was also the first senator to hire a female staffer and, as appropriations chairman during World War I, he was instrumental in funding the American efforts.