Weston was condemned to death, together with George Boleyn, Viscount Rochford, Henry Norris, William Brereton and Mark Smeaton.

He was the only son of Sir Richard Weston (1465–1541), KB, of Ufton Court in Berkshire and Sutton Place in Surrey,[3] a prominent courtier and diplomat who served under King Henry VIII as Governor of Guernsey, Treasurer of Calais and Under-Treasurer of the Exchequer.

Anne told one of these ladies, Mistress Coffin, that she had reprimanded Weston for flirting with Madge Shelton, who was betrothed to his fellow courtier Henry Norris.

Francis was executed at the age of twenty-five after being accused of committing adultery with Queen Anne Boleyn, treason and plotting to kill the king.

[8] Francis was beheaded on Tower Hill on 17 May 1536 along with his co-accused, George Boleyn, Viscount Rochford; William Brereton; Henry Norris and Mark Smeaton.