1540, Portugal – December 8, 1596, Mexico City) was a Marrana (Crypto-Jew) in New Spain executed by burning at the stake by the Inquisition for judaizing in 1596.
Another son, Gaspar, a pious young man, perhaps a monk, in the convent of Santo Domingo, Mexico, had arrived a short time before.
The entire family then removed to the capital, where, in the year 1590, while in the midst of prosperity, and seemingly leading Christian lives, they were seized by the Inquisition.
During their imprisonment they were able to communicate with one another with Spanish pear seeds, on which they wrote messages of encouragement to remain true to their faith.
They were found out and at the resulting auto-da-fé, Doña Francisca and her children, Isabel, Catalina, Leonor, and Luis, were burned at the stake, together with Manuel Díaz, Beatriz Enríquez, Diego Enríquez, and Manuel de Lucena, being accused of relapsos, term used to those repeatedly accused of judaizing.