In Congress he stood out for being the senator with more laws passed in the 2006–2010 four-year period; made significant contributions to the Constitution of the Republic proclaimed in the year 2010 and received wide acceptance for managing a vast cultural and educational agenda in favor of its province Santiago.

As Prosecutor of the National District and Attorney General of the Republic he pursued and obtained significant convictions in crimes that moved Dominican society in the last decades of 20th century and promoted an institutionalization program for criminal and prison prosecution systems.

In the private sphere, he has been a legal advisor to the Chamber of Deputies of the Republic, professor of 'History of Political Ideas' at PUCMM, Director Executive of the Institutional and Justice Foundation (FINJUS), as well as a consultant to the National School of the Magistracy in relation to the Program of Implementation of the New Criminal Procedure Code; of the State Reform and Modernization Support Project (PARME), which operates with funds from the European Union; and of the Judicial Statistics Research Project implemented by the Justice Studies Center of Las América (CEJAS) whose headquarters are located in Santiago, Chile, among other institutions.

In the private sector, he has been a legal advisor to the Chamber of Deputies of the Dominican Republic, a professor of "History of Political Ideas" in the Pontifice Universidad Catolica Madre Maestra (PUCMM), and Executive Director of Institutional and Justice Foundation (FINJUS).

He has also been a consultant to the National Judicial School regarding the Program to Implement the New Criminal Procedure Code, the Project for the Reform and Modernization of the State (Parma), which operates with funding from the European Union and Research Project on Judicial Statistics implemented by the Justice Studies Center of The Americas (CEJAS) headquartered in various locations including Santiago, Chile.

In the Prosecutor's Office of National District, Francisco Domínguez Brito promoted profound reforms both in the organizational aspect and in the direction of the criminal investigation to make the entity a modern institution, with clear and transparent procedures.

A database and effective control of detainees was initiated through a systematic procedure for registering and identifying them by capturing biometric data from the moment they entered the judicial system.

In this way, the Public Ministry (Ministerio Público [es]) assumed control of the investigations from the moment he was aware of the criminal offense, generating a coordinated and immediate reaction.

Finally, under the direction of Domínguez Brito, the Office of the National District gave priority to an extensive program of alternative dispute resolution.

With this program, conciliation between the parties was sought in cases in which the public interest and citizen security were not compromised, thereby ending the conflict through the agreement, thus avoiding minor offenses from entering the judicial system.

By assuming Prosecutor a strategic plan was developed based on the analysis of the challenges presented to the Public Prosecutor's Office the New Criminal Procedure Code (approved two years earlier), the implementation of the Statute of the Public Ministry (approved a year earlier), its interrelation with the other entities of the Justice System and society.

[5] From here, they promoted important initiatives related to the regulation of the state procurement and contracting regime, first through a Presidential decree and then through the bill that would later govern the matter.

In this sense, the highest percentage of the resources administered by the Senate office was dedicated to this chapter through relevant activities and events, among which are: Source:[8] In the framework of the reform process to the constitution Dominican initiated in the year 2008, and after the approval of the law that declared the need for Congress to avoid these tasks, the November 12, 2008 Francisco Domínguez Brito presented the preliminary proposal of the report regarding the Convocation Bill for Constitutional Reform, which supported the constitutional reform as a result of The need for institutional strengthening, the establishment of criteria for incorporating international standards into domestic law, the extension of constitutional procedures that allow the system of weights and balances to be efficient, the consolidation of the rule of law and compliance with the law, of the scope of transparency in the actions of the administration, of guaranteeing economic democracy through an instrument for the integral development of the nation Ion: the person, the family and society, and finally the substantive rule reform is supported by the need to incorporate new legal figures.

In this sense, he used important public scenarios to express his vision about the need to strengthen institutionality and horizontal control mechanisms among the Powers of the State of the Republic, as well as for the establishment of more and better systems.

[10] Style Commission Coordinator The Constitution Review Assembly met for the first time on Tuesday March 24 of the year 2009 in Santo Domingo.

As president of the Special Commission on the Judiciary, he proposed a new redesign of judicial organization, powers, and prerogatives of the justice system actors in the Republic.

Domínguez Brito along with the assembly members of the PLD Minou Tavárez Mirabal and Julio César Valentín Jiminián managed to approve more than a third of the 277 articles of the new Constitution of the Republic proclaimed in the year 2010.

On August 22, 2011, the President of the Dominican Republic Leonel Fernández appointed Francisco Domínguez Brito as Minister of Labor through decree number 494-11.

During the performance of their duties, during the management of Francisco Domínguez Brito, 6,590 users were served, of which 1,395 received an assignment of lawyers for cases in the courts of the republic: 688 for dismissals, 305 for resignations and 400 for eviction.

In July 2012, an agreement was signed with the Attorney General's Office, in order to establish an inter-institutional cooperation scheme aimed at promoting the social and labor reintegration of the users of the Free Environment (formed by people who have come out of serving sentences from the new prisons in the country), as well as deported people, through the creation and identification of job opportunities that allow them to generate income to support themselves with their families.

In the period from August 2011 to July 2012, 341 training courses were held with 119 System Operational Centers (COS) for a total of 10,980 young beneficiaries.

The "Santiago Trabaja" Project constituted one of the four components of the Youth Development Program that the Ministry of Labor has executed since 2007, with the support of the World Bank.

Eleven (11) days after assuming as Attorney General for the second time, Francisco Domínguez Brito announced that after an investigation led by the Inspectorate of the Procuraduría, it was determined that Pascual Cordero Martínez paid more than one million pesos for the prison director, Mario Acosta Santos, to manage to return him to the "La Victoria" Jail from the Higüey Correction and Rehabilitation Center where he was transferred to have more control of him by the rigor of the New Penitentiary Model.

Likewise, Carmen Elizabeth Jiménez, Fernando Arturo Martínez Ramos, Ana Cristina Rodríguez, Máximo Peralta and Leiny Rosario Solís, from La Vega.

On September 14, the Attorney General presented to the National Congress a proposal to amend the Criminal Procedure Code to limit some situations that have allowed prosecuted persons to evade justice, as well as to limit the discretion of judges when imposing coercive measures on repeat offenders or other pending legal proceedings, create a more efficient system for the capture of fugitives or declared in absentia, among others.

[20] Through a communication sent to the director of Prisons, Tomás Holguín La Paz, Domínguez Brito issued instructions so that no inmate enjoys special privileges, such as the use of air conditioners, televisions, antennas Satellite dishes, laptops, phones, among others.

The Attorney General of the Republic instructed all representatives of the Public Ministry to only seize motor vehicles when they constitute a probative and binding element with the process that takes place.

He pointed out that the warning was given to preserving the fundamental right of ownership inherent in every person, which may be violated at the time of kidnapping things, especially motor vehicles.

On October 22, 2014, Francisco Domínguez Brito sent an indictment and opening request to trial against Senator Felix Bautista deposited with the Supreme Court of Justice.

[23] The Office of the Prosecutor requested the appointment of a Judge of Instruction Special, to $2know in preliminary hearing a request for preventive detention and accusation for serious acts of corruption and money laundering against: Félix Ramón Bautista Rosario, Soraida Antonia Abreu Martínez, José Elías Hernández García, Bolívar Antonio Ventura Rodríguez, Carlos Manuel Ozoria Martínez, Gricel Aracelis Soler Pimentel and Welcome Apolinar Bretón Medina.