Francisco Mendoza de León (born June 11, 1947), is a Filipino prelate of the Catholic Church who served as Bishop of Antipolo from 2016 to 2023.

[1] De León was born June 11, 1947, in La Huerta, Parañaque, Philippines.

He served as an assistant parish priest of Santa Clara de Montefalco Parish in Pasay for two years before he was appointed director of studies, then prefect of discipline and finally rector at Our Lady of Guadalupe Minor Seminary.

[1] On January 25, 2013, Bishop de León was appointed as the Apostolic Administrator of the Diocese of Kalookan after the resignation of Deogracias Iñiguez Jr. due to his health condition.

On July 22, 2023, de León accepted his resignation upon the installation of his successor Ruperto Santos.