Francisco Ramón de Vicuña Larraín (Latin American Spanish: [fɾanˈsisko raˈmom biˈkuɲa]; September 9, 1775 – January 13, 1849) was a Chilean political figure.

In the ensuing civil war between the conservative centralists and the liberal federalists, Pinto was forced twice to leave the post of president to Vicuña.

On December 7, 1829 the conservative troops under José Joaquín Prieto Vial approached Santiago from the South.

Then, Chile was without a leader for a few weeks (from December 7 to 24, 1829) until a Government Junta was organized and took control under José Tomás Ovalle.

Under the centralist governments of José Joaquín Prieto Vial and Manuel Bulnes, the liberal Vicuña could not hold any governmental positions.