His main research dealt with adhesives, including those used in the construction materials in the de Havilland Mosquito combat aircraft.

Beginning in 1953, Assumption College received its own charter to become an independent degree-granting institution and thereby ended its affiliation with the University of Western Ontario.

He was the first to teach pre-engineering courses, such as descriptive geometry, surveying, and mechanical drawing in the regular day program.

[5] DeMarco was the first to propose that growth and long-term financial viability could only be achieved through the creation of a non-denominational college, which would receive provincial grants.

[6] The eventual task of spinning off an autonomous non-denominational affiliate from a Catholic university was a very complex undertaking, and was the culmination of over two years of negotiations.

LeBel and Reverend Norbert J. Ruth,[7] are considered the three central figures in the founding of Essex College.

From the beginning, DeMarco promoted his vision for the development of a complete academic experience of degree programs, graduate work, and research at the young Essex College.

Originally offering degrees in mathematics and sciences, Essex College later on added engineering, nursing and business.

As head of Essex College, DeMarco was able to considerably expand the resources available, and oversaw a very ambitious building and hiring program.

He was an innovator in the establishment of advisory boards and forums that gave guidance and feedback to University leaders and policy makers in whether curriculum content was evolving in concert with industry and society's needs.

DeMarco also made a significant imprint on many other aspects of education in the Windsor community: as founding chair of the Board of Governors of St Clair College of Applied Arts and Technology (1967–68), elected member of the Essex County School Board, President of the Greater Windsor Foundation (1976–77), member of a number of industry-based scholarship selection committees and other community initiatives.

In 1943 he pitched for Coppercliff Redmen in the Nickel Belt Baseball League when they won Northern Ontario Sr. "A" Championship.