Frank Annunzio (January 12, 1915 – April 8, 2001) was an American politician from Chicago, Illinois.

Annunzio, an Italian-American, was born in Chicago, where he remained for his entire childhood and much of his adult life.

He then had careers as a high school teacher and labor leader of the United Steelworkers of America.

In 1989, he urged people to burn credit cards in order to drive down interest rates and stop themselves from going into debt.

Annunzio died in 2001 in Chicago from complications arising from Parkinson's disease and was interred in the Queen of Heaven Cemetery.