He began his acting career in the 1930s, when he and longtime friend Lloyd Bridges performed in summer stock theater at a playhouse in Weston, Vermont.

Latimore then went to Hollywood where he signed a contract with 20th Century-Fox, and proceeded to appear in such hits as In the Meantime, Darling, The Dolly Sisters, Three Little Girls in Blue, and Shock.

Latimore appeared in two soap operas, playing Dr. Ed Coleridge on Ryan's Hope from 1975 to 1976, and Dr. Emmet Scott on Guiding Light from 1976 to 1979.

While working in Rome, Italy, in the late 1940s, Latimore met and married Russian-born Valentina Nikitina (12/24/1920 - 3/8/2009) in 1948.

His remains were cremated and buried beneath a venerable old apple tree on ancestral property in Vermont.