He was born in the town of Clarksburg, West Virginia in Harrison County and was a three sport athlete at Notre Dame Catholic High School.

[3] Loria played safety in the same defensive backfield with Frank Beamer, former head coach at Virginia Tech.

[5] In October 1966 against a ranked Florida State team Frank Loria returned a punt 80 yards for a touchdown that would prove to be significant in a 23-21 Virginia Tech victory.

[6] Loria also made the game deciding 4th down tackle on a FSU running back on the goal line.

Frank Loria made a critical 4th quarter interception that preserved the victory for Virginia Tech by the score of 20-18.

[9] In December 1966 the 8-1-1 Virginia Tech Hokies would face the 9th ranked 7-2-1 Miami Hurricanes in the Liberty bowl.

Loria was inducted into the College Football Hall of Fame on December 7, 1999, along with the man he played for, former Virginia Tech Coach the late Jerry Claiborne.

The local Clarksburg Columbian Club honors his memory every year by hosting the Frank Loria Dinner, where the first team All Harrison County football players attend.