Simes is the musical director for Roger Daltrey, and has recorded and performed with Mick Jagger, Don Henley, and Stevie Nicks.

The second and younger son of Stephen Hardy Simes, legal attaché to General Douglas MacArthur and judge advocate at US Army Japan, and Japanese model and restaurateur, Sachiko Nakamura.

His professional career began at 14 when his band, Sunrise, which he formed with Mickie Yoshino and Steve Fox, later of Godiego released a record on RCA Victor.

At 20, his band, the Whizz Kidds, was signed by Highland/A&M Records, and Frank's song, "Sweet Honey", their debut single, received national airplay.

During the next two decades, Simes also worked with Rod Stewart, Don Felder, Charlotte Church, Sylvie Vartan, Engelbert Humperdinck, David Lee Roth, Warren Zevon and Roger Waters.

Simes has also composed original guitar and piano pieces in the Modern, Baroque, and Romantic styles, some of which were recorded by the London Philharmonic Orchestra.

Frank Simes is the recipient of nine platinum records with such artist as Don Henley, Rod Stewart and various soundtrack albums.